ISSN 2312-3672
Andreev V., Zachinyaeva A., Sobolev P., Mukhina N. Acetylenic quaternary ammonium salts having bactericidal and fungicidal properties // Journal of Biomedical Technologies. 2015. № 1. P. 29‒33. DOI: 10.15393/j6.art.2015.3281
Issue № 1 (2015)
Brief Communications
Acetylenic quaternary ammonium salts having bactericidal and fungicidal properties
| Andreev Vladimir Petrovich | Petrozavodsk State University, 33, Lenin Str., 185910, Petrozavodsk, Republic of Karelia, Russia, a-alex@rkmail.ru |
| Zachinyaeva Anna Vladimirovna | S.M. Kirov Military Medical Academy, 6, Academic Lebedev St., 185910, St. Petersburg, Russia, anvzanna@aol.com |
| Sobolev Pavel Sergeevich | Petrozavodsk State University, 33, Lenin Str., 185910, Petrozavodsk, Republic of Karelia, Russia, 16862.10.ns@gmail.com |
| Mukhina Natalya Ilinichna | Petrozavodsk State University, 33, Lenin Str., 185910, Petrozavodsk, Republic of Karelia, Russia, natashamukhina944@gmail.com |
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monoacetylenic quaternary ammonium salts; antimicrobial bactericidal and fungicidal activity; disinfection |
By disco-diffusion method it was shown that monoacetylenic quaternary ammonium salts have weaker, but more selective bactericidal and fungicidal activity against the Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Proteus vulgaris, Proteus mirabilis, Penicillium spp. and Bacillus cereus microorganisms, than trioctylmethylammonium iodide and diacetylenic dioctyldi(hept-2-ynyl)ammonium bromide, which do not contain a triple bond. Only trioctyl(hept-2-ynyl) ammonium iodide was active against Saccharomyces cerevisiae. |
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