| Borisova Marya Igorevna  | Petrozavodsk State University, 33, Lenin str., Petrozavodsk, Russia 185910, fagafon@yandex.ru | 
| Lazakovich Dmitry Nikolaevich  | Petrozavodsk State University, 33, Lenin str., Petrozavodsk, Russia 185910, dim.lazackovich@yandex.ru | 
| Sidorova Natalia Anatolievna  | Petrozavodsk State University, 33, Lenin str., Petrozavodsk, Russia 185910, vanlis@petrsu.ru | 
| Savushkin Andrey Ivanovich  | The Karelian Republic Branch of «Gossortkomissiya», 5, L. Tolstoy str., Petrozavodsk, Russia, 185005, fagafon@yandex.ru | 
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			biofilms persisters TA-system Staphylococcus aureus clinical manifestations.  | 
		
			The paper dwells on modern ideas of biofilm structure and mechanisms of its formation. Biofilm is a special form of microflora organization in conditionally pathogenic and pathogenic microorganisms involved in emergence and development of diseases of both infectious and somatic etiology. Taking the biofilm-forming activity of Staphylococcus aureus as an example, the phenomenon of microorganisms tolerance mediated by SasG-protein and the ability of microorganisms to form persister cell populations is considered. |