ISSN 2312-3672
Borisova M., Lazakovich D., Sidorova N., Savushkin A. Biofilm-forming activity and the phenomenon of persistense in microorganisms // Journal of Biomedical Technologies. 2015. № 2. P. 28‒35. DOI: 10.15393/j6.art.2015.3382
Issue № 2 (2015)
Analytical review
Biofilm-forming activity and the phenomenon of persistense in microorganisms
| Borisova Marya Igorevna | Petrozavodsk State University, 33, Lenin str., Petrozavodsk, Russia 185910, fagafon@yandex.ru |
| Lazakovich Dmitry Nikolaevich | Petrozavodsk State University, 33, Lenin str., Petrozavodsk, Russia 185910, dim.lazackovich@yandex.ru |
| Sidorova Natalia Anatolievna | Petrozavodsk State University, 33, Lenin str., Petrozavodsk, Russia 185910, vanlis@petrsu.ru |
| Savushkin Andrey Ivanovich | The Karelian Republic Branch of «Gossortkomissiya», 5, L. Tolstoy str., Petrozavodsk, Russia, 185005, fagafon@yandex.ru |
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biofilms persisters TA-system Staphylococcus aureus clinical manifestations. |
The paper dwells on modern ideas of biofilm structure and mechanisms of its formation. Biofilm is a special form of microflora organization in conditionally pathogenic and pathogenic microorganisms involved in emergence and development of diseases of both infectious and somatic etiology. Taking the biofilm-forming activity of Staphylococcus aureus as an example, the phenomenon of microorganisms tolerance mediated by SasG-protein and the ability of microorganisms to form persister cell populations is considered. |
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