ISSN 2312-3672
Gradov O., Adamovich E. MICROGRAVITATIONAL NEUROGONIOMETRY AS A NOVEL MEASUREMENT TOOL FOR THE COMPLEX MORPHOFUNCTIONAL, MORPHOBIOCHEMICAL AND MORPHOPHYSIOLOGICAL STUDIES OF THE NEURON BIOPHYSICAL STATE IN SPACE CONDITIONS FOR EXPERIMENTS ON BIOSATELLITES // Journal of Biomedical Technologies. 2017. № 1. P. 25‒29. DOI: 10.15393/j6.art.2017.3764
Issue № 1 (2017)
Brief Communications
MICROGRAVITATIONAL NEUROGONIOMETRY AS A NOVEL MEASUREMENT TOOL FOR THE COMPLEX MORPHOFUNCTIONAL, MORPHOBIOCHEMICAL AND MORPHOPHYSIOLOGICAL STUDIES OF THE NEURON BIOPHYSICAL STATE IN SPACE CONDITIONS FOR EXPERIMENTS ON BIOSATELLITES
| Gradov Oleg V. | Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, 38/2 Leninsky prospekt, Moscow, Russia 119334, gradov@center.chph.ras.ru |
| Adamovich Eugeny D. | Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, 38/2 Leninsky prospekt, Moscow, Russia 119334, gradoff@bioinformatics.ru |
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microgravitation minimal surfaces orbital station biosatellites spherical surfaces |
The effect of weightlessness / microgravity on the characteristics of the charge transfer across the neuron membrane is well known in space biology and medicine. In the absence of any gradients determining the growth directions of the neurites the neuron has a spherical shape characterized by the minimal surface. From the standpoint of functional morphology, it seems reasonable to design a system for a simultaneous monitoring of the electrobiophysical / electrophysiological and neuromorphological state of the brain neuronal structure, nervous tissue culture or the living slices directly in the microgravity / weightlessness conditions during the space flight. We have earlier developed a five-axis robotic positioning system for measurements on the living slices and tissue cultures, which demonstrated the dependence of the certain structure morphogenesis on its orientation in the gravitational field and external fields, as well as its correlation with the directed electrophysiological activity. The above system can be easily adapted to the astrophysical microgravity conditions. |
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